Journal of Nature and Science of Medicine

SYSTEMATIC REVIEW
Year
: 2022  |  Volume : 5  |  Issue : 2  |  Page : 85--97

Pneumothorax as a complication of COVID-19: A systematic review of individual patients' characteristics


Abdulrahman Mutlag Almalki1, Murouj Adnan Almaghrabi1, Ahmad Hamed Alharbi1, Ahaad Mohammad Basahal1, Bashaer Ayidh Alharbi1, Mohammad Alfelali2, Mohammed Shabrawishi3 
1 Department of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah, Saudi Arabia
2 Department of Family and Community Medicine, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia
3 Department of Respiratory Medicine, Al-Noor Specialist Hospital, Makkah, Saudi Arabia

Correspondence Address:
Murouj Adnan Almaghrabi
Department of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah
Saudi Arabia

Since the coronavirus disease-2019 (COVID-19) outbreak in December 2019, evidence suggests an association between COVID-19 and the onset of pneumothorax (PTX). Thus, the present study aimed to investigate the onset of PTX, the possible risk factors, clinical characteristics, management, prognosis, and mechanism of PTX formation in patients with COVID-19 infection. A systematic review was done using several databases for articles published from December 2019 to January 2021. One-hundred and thirty-nine patients in a total of 87 articles fulfilled our criteria. A broad age range was affected (mean and standard deviation of 57 ± 15.39) with male predominance (77.7%). Most patients (66.2%) developed PTX during the hospital stays. In those who developed PTX, the most recognized characteristics included male gender (77.7%), severe COVID-19 infection (41%), mechanical ventilation (43.2%), age >65 years (30.9%), other diseases (79.1%), and smoking (8.6%). A good prognosis was reported in more than half of the patients (83; 59.7%). Death was significantly associated with critical conditions of COVID-19, bilateral PTX, respiratory distress, and mechanical ventilation (P = 0.006, 0.001, 0.013, and 0.001, respectively). PTX is a potential complication of COVID-19 infections, commonly noticed in the right lung. Mechanical ventilation, COVID-19 severity, bilateral PTX, and acute respiratory distress were associated with worse outcomes in COVID-19 patients with PTX.


How to cite this article:
Almalki AM, Almaghrabi MA, Alharbi AH, Basahal AM, Alharbi BA, Alfelali M, Shabrawishi M. Pneumothorax as a complication of COVID-19: A systematic review of individual patients' characteristics.J Nat Sci Med 2022;5:85-97


How to cite this URL:
Almalki AM, Almaghrabi MA, Alharbi AH, Basahal AM, Alharbi BA, Alfelali M, Shabrawishi M. Pneumothorax as a complication of COVID-19: A systematic review of individual patients' characteristics. J Nat Sci Med [serial online] 2022 [cited 2022 Jun 29 ];5:85-97
Available from: https://www.jnsmonline.org/article.asp?issn=2589-627X;year=2022;volume=5;issue=2;spage=85;epage=97;aulast=Almalki;type=0