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Year : 2021  |  Volume : 4  |  Issue : 3  |  Page : 303-308

Polycystic ovarian syndrome and diabetes mellitus: What's new?

Department of Internal Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia

Correspondence Address:
Riad A Sulimani
Department of Internal Medicine, College of Medicine, King Saud University, Riyadh
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jnsm.jnsm_140_20

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Polycystic ovarian syndrome (PCOS) is an important public health problem. In addition to its gynecologic and hyperandrogenic manifestations, it has been associated with an increased incidence of prediabetic state, gestational diabetes mellitus (GDM), and diabetes mellitus. The pathogenesis of PCOS, as well as its metabolic consequences, is complex. The two main causative factors are intrinsic insulin resistance and impaired β cell function. Obesity has frequently been reported in PCOS; however, it is not entirely responsible for the insulin resistance in this population. PCOS should be managed with lifestyle modifications and appropriate dietary measures. In addition, treatment with insulin sensitizers is usually needed. PCOS provides a unique opportunity for the screening and early diagnosis of diabetes and its management.

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